19 Facts You Need to Know About Mounjaro

Reviewed by:
Independent Prescribing Pharmacist
GPhC registration number: 2219022

Mounjaro (tirzepatide) is making a big impact on diabetes treatment and weight management. This medication has been gaining attention for its impressive results, but there’s a lot to understand about how it works and why it’s becoming so popular.

We’ve rounded up key facts and statistics that highlight the most important details about Mounjaro. From its approval process to its effectiveness in aiding weight loss to managing diabetes, these facts will give you a clear picture of what Mounjaro offers.

Whether you’re considering Mounjaro as a treatment option or are just interested in the latest advancements in diabetes care, these facts and statistics will provide the key information.

Stay informed and discover the most up-to-date research and real-world data surrounding Mounjaro. We’ve gathered everything you need to know about this medication in one place.

1. First 12 Weeks: Average weight loss is 8% of initial body weight by week 12.

Source:https://www.numan.com/weight-loss/medication/how-quickly-results-mounjaro

2. Week 24: Average weight loss is between 12-15% of initial body weight.

Source: https://www.numan.com/weight-loss/medication/how-quickly-results-mounjaro

3. Weeks 24-72: Weight loss increases to between 16-22% of initial body weight, depending on dosage.

Source: https://www.numan.com/weight-loss/medication/how-quickly-results-mounjaro

4. Overall Average: After 72 weeks, the average weight loss ranges from 15% to 22% of initial body weight when combined with a healthy diet and exercise.

Source: https://www.numan.com/weight-loss/medication/how-quickly-results-mounjaro

5. Treatment Duration: The study tracked weight loss over 72 weeks (approximately 1.5 years).

Source: https://www.numan.com/weight-loss/medication/how-quickly-results-mounjaro

6. Patients who stopped the drug regained 14% of their body weight within 52 weeks.

Source: https://onlinedoctor.asda.com/uk/keep-weight-off-after-mounjaro.html

7. 90% of patients who stayed on tirzepatide maintained at least 80% of their weight loss.

Source: https://gi.org/journals-publications/ebgi/schoenfeld2_feb2024/

8. Mounjaro works by mimicking GLP-1 and GIP gut hormones, enhancing satiety, slowing digestion, and regulating blood sugar.

Source: https://www.diabetes.org.uk/about-diabetes/looking-after-diabetes/treatments/tablets-and-medication/glp-1/mounjaro

9. Higher doses (10 mg and above) typically lead to more substantial weight loss compared to lower doses.

Source: https://www.drugs.com/medical-answers/why-losing-weight-mounjaro-3577543/

10. Patients who combined Mounjaro with intensive lifestyle changes achieved up to 26% total weight loss, emphasising the role of behavioural modifications

Source: https://www.medicalnewstoday.com/articles/mounjaro-helped-produce-26-loss-in-body-weight-for-people-with-obesity

11. Mounjaro is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, making it the first medication to target both pathways for metabolic benefits.

Source: https://www.medwayswaleformulary.co.uk/media/1753/tirzepatide-factsheet.pdf

12. Mounjaro significantly reduces appetite, leading to a natural calorie deficit and aiding in weight loss.

Source: https://www.secondnature.io/guides/lifestyle/glp1s/how-mounjaro-works-for-weight-loss

13. Mounjaro is administered via a once-weekly injection, making it a convenient option for long-term use.

Source: https://www.diabetes.org.uk/about-diabetes/looking-after-diabetes/treatments/tablets-and-medication/glp-1/mounjaro

14. Head-to-head trials showed Mounjaro resulted in 5% more weight loss compared to semaglutide (Wegovy/Ozempic) at comparable doses.

Source: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2821080

15. Common side effects include nausea, diarrhoea, and vomiting, often mild and improving over time.

Source: https://www.medicalnewstoday.com/articles/drugs-mounjaro-side-effects

16. Mounjaro is not yet widely available on the NHS for weight loss. However, discussions are ongoing about its potential inclusion in NHS obesity treatment programmes once approved for this use.

Source: https://www.bbc.co.uk/news/articles/cx2y5zl99vro

17. UK residents often access Mounjaro through private healthcare providers or weight-loss clinics while awaiting broader NHS approval for weight management.

18. UK prescriptions start at 2.5 mg per week, gradually increasing to as much as 15 mg, ensuring tolerability and effectiveness.

19. Significant weight loss from Mounjaro is linked with improved mental health and quality of life, with a 50% reduction in depressive symptoms in some patients.

Source: https://www.healthline.com/health-news/glp-1-drugs-like-ozempic-and-mounjaro-linked-to-lower-risk-of-depression

Mounjaro is quickly becoming an important option for managing type 2 diabetes and supporting weight loss, with promising results seen in both clinical trials and real-world use.

As more research emerges, it’s clear that Mounjaro has the potential to make a significant difference in the lives of many. If you’re thinking about starting treatment with Mounjaro or simply want to learn more, these facts should help you get a clearer picture.

Interested in Mounjaro weight loss injections? Complete a questionnaire with us and receive an instant eligibility answer.

AUTHORED BY
Picture of Gurpreet Singh Bassi
Gurpreet Singh Bassi

Gurpreet is a qualified independent prescribing pharmacist with a number of years of experience across the pharmacy and healthcare sector. He is registered with the General Pharmaceutical Council to prescribe. His GPhC registration number is: 2219022

View All Posts
[acf_category_field]