How to Reduce Mounjaro Injection Side Effects

Reviewed by:
Independent Prescribing Pharmacist
GPhC registration number: 2219022

Mounjaro is a widely prescribed medication used to help manage diabetes and support weight loss. While it has proven to be effective in many patients, like many medications, it can cause a range of side effects. These side effects can vary in intensity and may cause discomfort, especially during the early stages of treatment.

Managing these side effects is key to patients staying on track with their treatment, allowing them to continue benefiting from Mounjaro. In this article, we will look at some of the most common side effects of Mounjaro injections and provide practical tips and strategies to help you manage them effectively. 

From managing nausea and constipation to addressing heartburn and hair loss, this guide aims to help you feel more comfortable and confident as you continue your treatment.

Nausea

mounjaro nausea

Nausea is one of the most common side effects when starting Mounjaro injections, especially as your body adjusts to the medication. While it can be uncomfortable, there are ways to manage nausea from Mounjaro and minimise its impact.

One effective strategy is to eat smaller, more frequent meals throughout the day, which can help prevent your stomach from becoming overly full and triggering nausea. It’s also wise to avoid foods that are spicy, greasy, or strong-smelling, as these can worsen the feeling of nausea. Staying hydrated is equally advised—sip on small amounts of water or herbal teas regularly to keep your fluid levels up without overwhelming your stomach.

By following these simple steps, many people find that their nausea gradually improves as they continue their treatment.

Constipation

Constipation is another common side effect of Mounjaro, largely because the medication can slow down digestion. If you’re experiencing this, there are several simple ways to achieve Mounjaro constipation relief.

Increasing your intake of dietary fibre is a great first step. Foods like fruits, vegetables, and whole grains can help add bulk to your stool and make it easier to pass. Alongside this, it’s essential to drink plenty of water throughout the day, as this helps soften stools and supports overall digestion. 

Regular light physical activity, such as walking, can also stimulate your digestive system and relieve constipation.

Diarrhoea

While less common, some individuals experience diarrhoea as their body adjusts to Mounjaro. If you find this happening to you, there are a few strategies that can help ease the symptoms.

Limiting high-fat or high-sugar foods is key, as these can aggravate diarrhoea and prolong discomfort. It’s also advised to stay hydrated, but focus on drinking fluids that contain electrolytes, such as oral rehydration solutions or coconut water, to prevent dehydration. 

In some cases, over-the-counter anti-diarrhoea medications can be helpful, but it’s always best to consult your doctor before taking any new medications to make sure they won’t interfere with your treatment.

Heartburn

heartburn mounjaro

Heartburn from Mounjaro can occur as a result of acid reflux, and for some Mounjaro users, this is a frustrating side effect. The good news is that there are practical steps you can take to help prevent it.

One effective strategy is to avoid lying down immediately after eating, as this can trigger acid reflux. Instead, try to stay upright for at least a couple of hours after meals. Eating smaller, more frequent meals throughout the day can also reduce the likelihood of heartburn, as large portions can increase stomach acid production. Additionally, identifying and avoiding common heartburn triggers, such as caffeine, chocolate, and acidic foods like tomatoes, can make a big difference in managing symptoms.

Itching

Itching at the injection site is a relatively minor side effect that some Mounjaro users experience. While this can be irritating, there are easy ways to reduce the discomfort.

A cold compress applied to the area can help soothe the skin and reduce both itching and swelling. If the itching persists, you can try using an over-the-counter hydrocortisone cream to calm the irritation. It’s also helpful to rotate your injection sites regularly, as this prevents repeated irritation to the same area, which can worsen the itching.

By taking these steps, injection site itching can often be minimised and become less of a concern over time.

Low Blood Pressure 

Mounjaro low blood pressure can be an unexpected side effect for some users, leading to symptoms such as dizziness or fainting. While this can be concerning, there are simple ways to manage it.

One strategy is to take your time when getting up from a seated or lying position, as standing up too quickly can cause dizziness. If you experience frequent dizziness, your doctor may recommend wearing compression stockings to help improve circulation. 

It’s also a good idea to monitor your blood pressure regularly, especially if you notice persistent symptoms, so you can discuss any changes with your healthcare provider.

Hair Loss

Although rare, some Mounjaro users may experience hair loss, which can be distressing. While this side effect isn’t common, it’s helpful to know how to manage it if it occurs.

Maintaining a balanced diet that’s rich in vitamins and minerals, particularly those that support hair health such as biotin, zinc, and iron, can help strengthen your hair and minimise loss. 

Additionally, adopting gentle hair care practices—such as avoiding harsh treatments like excessive heat styling or chemical products—can prevent further damage. If hair loss becomes significant, it’s advised to consult your doctor, as this could indicate the need for further investigation or alternative treatments.

By taking these steps, you can reduce the impact of hair loss and promote healthier hair growth.

Managing the side effects of Mounjaro injections is useful for staying on track with your treatment and improving your overall comfort. From tackling nausea and constipation to addressing heartburn and itching, there are many practical strategies you can adopt to reduce these common side effects.

While many of these symptoms improve as your body adjusts to the medication, it’s best to consult your healthcare provider if you experience persistent or severe side effects. 

By being proactive and following these tips, you can continue benefiting from Mounjaro while minimising discomfort, meaning that your treatment remains effective in the long run.

AUTHORED BY
Picture of Gurpreet Singh Bassi
Gurpreet Singh Bassi

Gurpreet is a qualified independent prescribing pharmacist with a number of years of experience across the pharmacy and healthcare sector. He is registered with the General Pharmaceutical Council to prescribe. His GPhC registration number is: 2219022

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