Interest in weight loss injection alternatives has increased as more people look for clinically supported ways to manage their weight.
With Mounjaro gaining attention, many now want to understand which Mounjaro alternatives exist and how they differ. Some people may not be suitable for Mounjaro, while others simply want to know about other weight management treatments.
Several options are available, including prescription medicines and over-the-counter choices, each with unique benefits and requirements.
Understanding how these treatments work can help support informed, safe discussions with a qualified healthcare professional.
Disclaimer: This article is for general informational purposes only. It is not intended to provide medical advice or replace a clinical assessment. Only a qualified healthcare professional can determine whether a particular weight management treatment is suitable for you.

Wegovy
When people look at Mounjaro alternatives, Wegovy is one of the best-known names. It belongs to a class of medicines called GLP-1 receptor agonists, which work by mimicking a natural hormone that helps regulate appetite and blood sugar levels.
You might often see comparisons between Wegovy vs Mounjaro, though they contain different active ingredients and are prescribed in different ways.
Wegovy is a prescription weight loss option that must be recommended by a qualified clinician. It is usually taken as a once-weekly injection alongside balanced eating and physical activity. The goal is to support gradual, supervised weight loss within a structured health plan.
Some people may find it suitable when other methods have not worked well, but a professional assessment is always essential before starting treatment. Side effects can occur and vary between individuals, most often affecting digestion. These are typically mild and can lessen over time.
Because Wegovy is a prescription-only medicine, it should never be used without medical oversight. Ongoing monitoring helps ensure safety and keeps treatment aligned with personal health goals. For most people, it works best as part of a broader weight management treatment plan rather than a standalone solution.
Orlistat
For those exploring alternatives to Mounjaro, Orlistat offers a different approach to weight management. Instead of affecting appetite, it works in the digestive system by blocking some of the fat eaten from being absorbed. The unabsorbed fat then leaves the body naturally.
Unlike injectable GLP-1 alternatives, Orlistat comes as a capsule and is available both on prescription and in lower-strength versions over the counter. It’s often chosen by people who prefer non-injectable weight management treatments or who are not suitable for GLP-1 medicines.
When used with a lower-fat diet and regular exercise, Orlistat for weight loss can support gradual progress. Side effects are usually digestive and linked to high-fat meals, often improving as eating habits adjust. A pharmacist or clinician can confirm whether Orlistat is appropriate and guide safe use within a personalised plan.
alli
alli is a well-known option among Mounjaro alternatives, offering a lower-strength, over-the-counter version of Orlistat for weight loss. It’s designed for adults with a body mass index (BMI) of 28 or above and works by preventing the body from absorbing some of the fat from food. That fat then passes naturally through digestion.
As an accessible, non-prescription choice, alli is intended to be used alongside a reduced-calorie, lower-fat diet. It should still be used under professional guidance, as pharmacists can advise whether it’s suitable based on personal health and any existing medications.
Mild digestive effects, such as changes in bowel habits, can occur but often settle as dietary fat intake decreases. When combined with balanced eating and activity, alli can form part of a safe, structured weight management treatment plan supported by healthcare advice.
Xenical
Xenical is the prescription-strength form of Orlistat, used by some people exploring alternatives to Mounjaro. It contains the same active ingredient as lower-dose Orlistat but is only available after a medical consultation. Because it’s a prescription weight loss option, a clinician must review your health, medications and overall suitability before prescribing it.
Like other forms of Orlistat, Xenical works by blocking a portion of dietary fat from being absorbed during digestion. The unabsorbed fat leaves the body naturally, helping to reduce calorie intake. Its effectiveness depends on maintaining a lower-fat diet and an active lifestyle, so healthcare professionals often recommend regular check-ins for support.
Common side effects are digestive and usually temporary, especially when dietary fat intake is moderate. Monitoring from a clinician helps manage any reactions and ensures safe, consistent progress.
Used correctly and alongside professional guidance, Xenical can be part of a wider weight management treatment plan aimed at long-term, steady results rather than short-term change.
Saxenda
Among the recognised Mounjaro alternatives, Saxenda is a once-daily injectable treatment from the same family of medicines known as GLP-1 receptor agonists. Comparisons such as Saxenda vs Mounjaro are common because both influence appetite and calorie intake, although they use different active ingredients and dosing schedules.
Saxenda is a prescription weight loss option that must be prescribed by a qualified clinician. It’s typically used alongside healthy eating and increased physical activity to support gradual, monitored weight loss. Healthcare professionals may recommend it for adults with obesity or overweight conditions linked to health risks, depending on individual circumstances.
Side effects can occur and vary between people, most often involving mild digestive symptoms. These are generally manageable with clinical supervision.
Like other GLP-1 alternatives, Saxenda works best as part of a holistic weight management treatment plan. Balanced nutrition, consistent movement and emotional well-being all contribute to long-term results. Regular follow-ups with a prescriber ensure safety and help tailor the treatment to personal health goals.

Choosing between Mounjaro alternatives depends on personal health, goals and professional advice. Each option, whether injectable or oral, works differently and carries its own considerations.
Treatments such as Wegovy, Saxenda and Orlistat for weight loss can all play a role in a safe, clinically supported weight management treatment plan. However, they should never replace healthy habits or be used without professional guidance.
If you’re considering weight loss injection alternatives or other prescription weight loss options, speak with a qualified clinician first. They can assess your medical history, discuss possible side effects and guide you toward suitable care.
At WePrescribe, consultations are discreet, straightforward and focused on safe, regulated treatment. Booking an online consultation is the best way to receive expert advice tailored to your health and long-term goals.
