Trimethoprim Tablets - UTI Treatment

E.coli is the most common bacteria that causes UTI's. Trimethoprim does not kill E.coli. It works by stopping bacterial DNA synthesis, meaning that the bacteria cannot replicate. This allows your immune system to destroy the infecting bacteria until they get eradicated and your infection gets resolved. The bacteria gets out of the body through the urinary tract when urinating. Symptoms including high temperatures and pain improve with 24-48 hours of taking Trimethoprim. However, you should complete the entire course to avoid bacterial resistance to the drug.

What is Trimethoprim used for?

Trimethoprim is used to treat urinary tract infections (UTIs) by stopping bacterial DNA synthesis.

How should I take Trimethoprim Tablets?

Trimethoprim tablets should be taken with a glass of water. The usual adult dose for a sudden infection is 200 mg twice a day, while for long-term prevention, the dose is typically 100 mg once a day. It's important to follow your doctor's instructions regarding dosage and duration.

Can Trimethoprim be taken during pregnancy or breastfeeding?

Trimethoprim is not recommended during the first 12 weeks of pregnancy due to its potential effect on folic acid levels, which are crucial for the baby's development. After the first 12 weeks, it can be taken if necessary, but always under medical advice. While breastfeeding, it is generally considered safe for short-term use, but long-term use should be discussed with a healthcare provider.

What are the common side effects of Trimethoprim?

Common side effects of Trimethoprim include nausea, vomiting, diarrhea, and headaches. Some people might also experience skin rashes or an increase in blood potassium levels. Serious allergic reactions are rare but require immediate medical attention if they occur.

Is it safe to drive or operate machinery while taking Trimethoprim?

There is no evidence to suggest that Trimethoprim affects your ability to drive or operate machinery. However, if you experience any side effects that impair your ability to concentrate or react, it is best to avoid such activities.

What precautions should I take when using Trimethoprim?

Avoid using Trimethoprim if you have a known allergy to it or any of its ingredients. It's also important to follow your doctor's instructions regarding dosage and duration of treatment to prevent recurrence or worsening of your condition. Regular blood tests may be necessary if you are on long-term treatment.

Can Trimethoprim interact with other medications?

Trimethoprim can interact with several other medications, including phenytoin (used for epilepsy), anticoagulants like warfarin, and diuretics (water tablets). Always inform your doctor of all medications you are taking to avoid potential interactions.

Avoid Trimethoprim for treating UTI infections if the following apply to you:

• - You are allergic to Trimethoprim.
• - You have liver or kidney problems.
• - You have folate deficiency.
• - You have hyperkaliemia.
• - You have galactose intolerance.
• - You are pregnant or breastfeeding.

Directions for Using Trimethoprim:

• - Trimethoprim is an oral medicine suitable for women over 18 years.
• - Take Trimethoprim 200mg tablets twice daily, one dosage every 12 hours until the prescribed course is complete.
• - Swallow the capsule with a glass of water.
• - The tablets are not affected by food or alcohol.

Your treatment contains 200mg of Trimethoprim per tablet. Each tablet also contains the inactive ingredients anhydrous lactose, colloidal silicon dioxide, magnesium stearate, sodium lauryl sulfate, sodium starch glycolate, and stearic acid.

Like all medicines, some patients experience unpleasant side effects when taking Trimethoprim. Even though the drug is generally well-tolerated, consult your healthcare professional if you experience:

• - Diarrhoea.
• - Nausea and vomiting.
• - Stomach upset.
• - Loss of appetite.
• - Changes in taste.
• - Headache.